Vasculopathy in COVID-19 and Pathogenesis of Cutaneous Vascular Malformations Abstract SARS-CoV-2-associated vasculopathy under hyperlipidemia and pathological progression of congenital vascular abnormalities in Port Wine Stains. In the first part, we will present our clinical data for the first discovery of dyslipidemia in COVID-19 patients which have been substantially recognized. Mechanistically, we have shown evidence of […]
Light + Sound: Peering into Brain Function and Metabolism Abstract Exploiting the optical absorption contrast of blood hemoglobin, photoacoustic microscopy (PAM) is an emerging technology for label-free imaging of the microvasculature, which plays an essential role in supplying oxygen to the biological tissue and maintaining the metabolic activity in vivo. The multi-parametric PAM developed in […]
Confocal Microscopy for the Evaluation of OcularSurface Disease Abstract Diagnosis and treatment of ocular surface disease represents a large proportion of the average ophthalmologist’s practice. However, this group of conditions is more heterogeneous and complex than the term “dry eye” conveys. Further investigation of the pathophysiologic mechanisms underlying these conditions are underway, and in […]
Laser Beam Shaping for Surgery and Microbiopsy Abstract Lasers are increasingly being used for surgery in a wide range of medical specialties due to their advantages over alternative surgical tools. Advantages include precise material removal, limited bleeding, and delivery through optical fibers enabling use in body cavities and for minimally invasive surgeries. Advancements in […]
Commercialization and searching for a business model: why is spinning technology out of a lab so challenging? Abstract In this talk, we will explore the four critical challenges of getting technology out of a lab. Dr. Arkilic, Chief Innovation Officer of UCI has spent his entire career in supporting getting technology out of Academic labs. […]
True multi-modality optical molecular imaging – where both modalities interact and work in harmony. Abstract The main goal of the molecular imaging community has been achieving higher resolution and better quantitative accuracy. For nearly two decades, I have been spending effort for the same purpose, mainly integrating optical imaging with anatomic imaging modalities such as […]
A Leadership Toolbox for Operationalizing Innovation at Your Institution Abstract In today’s challenging healthcare environment, the importance of innovation has never been greater. Every healthcare institution anduniversity strive to be innovative, but successful innovative cultures and programs are difficult to create and sustain especially in the busy and fast-paced healthcare settings. Creating an innovative culture […]
Numerical Modeling of Medical Ultrasound Abstract In the last two decades, we have witnessed substantial development in high intensity focused ultrasound (HIFU) for treating a broad spectrum of diseases and medical conditions. As a non invasive surgical modality that can reach deep tissue, HIFU has the potential to revolutionize therapy. Although there are many numerical […]
Ultrathin 3D-printed Imaging Devices Abstract Preclinical studies and clinical diagnostics increasingly rely on optical techniques to visualize internal organs. Miniaturised catheters or endoscopes are necessary for imaging small and/or delicate arteries. However, current lens fabrication methods limit the performance of these ultrathin devices, resulting in a poor combination of resolution, depth of focus and multimodal […]
Cardio-oncology; Cardiovascular diseases in cancer patients Abstract With more advances in cancer therapy, more patients are alive as cancer survivors than a decade ago. However, cardiovascular disease is the number one reason for mortality in these cancer free patients. Beside the conventional risk factors for cardiovascular diseases, radiation and chemotherapy and cancer specific immunotherapy contributes […]