Cell Mechanics by Light Abstract Living cells are active matter characterized by mechanical properties as stiffness and deformability and morphological parameters as shape and volume. Genetic or pathogenic modifications of […]
Translating an understanding of the cutaneous microenvironment into diagnostics and treatments for wounds, cancers, and inflammatory dermatoses Abstract Immune cells are the first responders to injury, pathogens, or malignancy. The […]
Hierarchical Strategies Towards Biointerfacing With Soft Optoelectronic Materials Abstract The applications of functional nanomaterials towards biological interfacing continue to emerge in various fields, such as in drug delivery and tissue […]
Fluorophores with a Genome: DNA-Stabilized Silver Clusters as a New Class of Tunable Fluorophores for Microscopy and Biosensing Abstract Because near-infrared (NIR) electromagnetic radiation penetrates much farther into biological tissues […]
Optical Dissection of Brain Capillary Function Abstract My laboratory uses in vivo multiphoton imaging and rodent models to shed light (quite literally) on regulation of cerebral blood flow. In particular, […]
Harnessing Physiological Forces to Drive Stem Cell Fate & Function Abstract I will be elaborating about how physical cues are crucial to embryonic development, morphogenic events, and tissue organization, but […]
Illuminating Biomarkers of Stroke with Diffuse Optical Spectroscopies Abstract Our research group specializes in the development and application of diffuse optical spectroscopies to study the brain. These non-invasive, light-based tools […]
Vasculopathy in COVID-19 and Pathogenesis of Cutaneous Vascular Malformations Abstract SARS-CoV-2-associated vasculopathy under hyperlipidemia and pathological progression of congenital vascular abnormalities in Port Wine Stains. In the first part, we […]
Light + Sound: Peering into Brain Function and Metabolism Abstract Exploiting the optical absorption contrast of blood hemoglobin, photoacoustic microscopy (PAM) is an emerging technology for label-free imaging of the […]
Lasers in Nano-Surgery and Nano-Medicine: Plasmonic Nanobubbles Abstract To improve the safety and efficacy of standards of care in diagnostics and treatment of clinically-challenging diseases including cancer, we combine the […]