Cardio-oncology; Advanced optoacoustic imaging methods for biomedical research and clinical diagnostics
Abstract
Optoacoustic imaging has achieved remarkable progress over the last decade, benefiting from coordinated developments in optical and ultrasound technology, probe chemistry, and imaging theory. The technique is increasingly attracting attention of the biomedical research community due to its excellent spatial and temporal resolution, centimeter scale penetration into living tissues, versatile endogenous and exogenous optical absorption contrast. State-of-the-art implementations of multispectral optoacoustic tomography are based on multi-wavelength excitation of tissues to visualize specific molecules within opaque tissues. As a result, optoacoustics can noninvasively deliver structural, functional, metabolic, and molecular information from living tissues.
The talk covers advances in optoacoustic microscopy and tomography instrumentation, reconstruction algorithms for ultrafast imaging, as well as synergistic combinations with fluorescence, magnetic resonance and ultrasound methods. Efforts are underway to explore potential of the technique in studying multi-scale dynamics of the brain and heart, monitoring of therapies, targeted molecular imaging applications and clinical diagnostics of patients in a number of indications, such as breast and skin lesions, inflammatory diseases and cardiovascular diagnostics.
Biography
Professor Daniel Razansky holds the Chair of Biomedical Imaging with double appointments at the Faculty of Medicine, University of Zurich and Department of Information Technologies and Electrical Engineering, ETH Zurich in Switzerland, where he also serves as Director of the joint Preclinical Imaging Center.
He earned degrees in Biomedical and Electrical Engineering from the Technion – Israel Institute of Technology and conducted postdoctoral research at the Harvard Medical School. Previously, he was Professor of Molecular Imaging Engineering at the Technical University of Munich and Helmholtz Center Munich in Germany.
The Razansky Lab pioneered a number of bio-imaging technologies that were successfully commercialized and put into use in research labs and clinical facilities across the globe, among them the multi-spectral optoacoustic tomography (MSOT) and hybrid optoacoustic ultrasound (OPUS). His research has been recognized by the German Innovation Prize and multiple awards from the ERC, NIH, SNF, DFG and HFSP. He is also Fellow of the IEEE, SPIE and Optica Societies.
