Matthew Brenner

Clinical Professor, Department of Medicine

Dr. Matthew Brenner is a clinical professor of medicine at the UC Irvine School of Medicine. He conducts research in pulmonary medicine, critical care, sleep apnea, and cyanide poisoning and antidotes at UCI Beckman Laser Institute & Medical Clinic.

Dr. Brenner’s research focuses on laser optical diagnostics for pulmonary and critical care applications, specializing in high-resolution optical coherence tomography imaging and frequency domain photon-migration diffuse optical spectroscopy diagnostics for critical care.

Dr. Brenner’s research lab team is a part of a pipeline for discovery of chemical warfare countermeasures against cyanide. To this end, they are validating promising new drug antidote candidates for cyanide poisoning in mammals. In addition, they aim to accelerate advanced hydrogen sulfide antidote agents for mass exposures, including worker exposures in the oil and gas industry.

He has been named a fellow of the American College of Chest Physicians and was selected to serve on the National Institutes of Health (NIH) expert panel for cyanide toxicity.  He has been recognized as an outstanding teacher and among America’s best doctors.

Dr. Brenner earned his B.S. in both biology and chemistry from the University of California, Irvine, and his M.D. from the University of California, San Diego (UCSD) School of Medicine. He interned and completed his residency at UCSD and completed fellowship training in pulmonary and critical care medicine at U.C. Irvine and the NIH.  He is certified by the American Board of Internal Medicine in critical care, internal medicine and pulmonary disease. Dr. Brenner is a co-inventor on five U.S. patents.

Research Interests
+ pulmonary medicine
+ critical care medicine
+ sleep apnea
+ cyanide poisoning and antidotes

  • Education

    B.S., Biology, Chemistry, UC Irvine
    M.D., UC San Diego

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