From Light to Sound: Imaging, Treating, and Building Tissues at Depth Abstract Integrating light and sound, our research weaves engineering innovations that map, treat, and ultimately engineer living tissues at depthsunreachable by conventional optical methods—spanning scales from single cells to whole organs. (1) Seeing deep with clarity and color. Our photoacoustic imaging (PAI) converts optical […]

Mapping cellular function with 3D single molecule tracking and super-resolution microscopy Abstract Cellular function is governed by the molecular organization and interactions at the nanoscale. In this talk I will demonstrate our recent developments for improved 3D single-molecule tracking of dynamics and super-resolution imaging of nanoscale structures throughout mammalian cells and showcase applications of our […]

Induced pluripotent stem cells and vascular organoids assemble capillary malformation phenotypes: insights and challenges Abstract Recent advances in induced pluripotent stem cell (iPSC) technology have transformed vascular malformation research by enabling the development of human-relevant, genotype-specific disease models. Patient-derived or genome-edited iPSCs can be differentiated into endothelial cells and assembled into three-dimensional vascular organoids that […]