Single molecule fluorescence approaches reveal that DEAD-Box RNA helicases cluster in dynamic hubs for protein synthesis initiation Abstract DEAD-box helicases, DDX3 and eukaryotic initiation factor 4A (eIF4A), play essential roles in translation initiation, cytoplasmic surveillance for foreign RNAs and in facilitating cellular stress response. Using multi-parameter confocal fluorescence burst spectroscopy, we discovered that sex chromosome-encoded […]
Body-Interfaced Biosensors Abstract The rise of personalized medicine is reshaping traditional healthcare, enabling predictive analytics and tailored treatment strategies. In this talk, I will discuss our progress in developing wearable, implantable, and ingestible electrochemical biosensors for real-time molecular analysis. These bioelectronic systems autonomously access and sample diverse body fluids—including sweat, interstitial fluid, gastrointestinal fluid, wound […]
Listening to the Sound of Light with A Robot: Fusion of Imaging and Robotics for Healthcare Abstract Medical robotics has been widely applied in areas such as surgical assistance, enabling higher precision, reduced fatigue, and enhanced performance, and tele-operation, allowing surgeons to perform procedures remotely without being physically present with the patient. A key enabler […]
