Dr. Bernard Choi Honored by ESC

Link to Engineering Announcement

BLI Medical Student Ed Wu Awarded ASLMS Research Grant

Ed Wu

The American Society for Laser Medical and Surgery (ASLMS) announced today that UCI School of Medicine medical student Ed Wu, who is in the MD MBA program, has just been awarded one of only four ASLMS Student Research Grants. The award of $5,000 will support Ed’s research project, “Laser Auricular Cartilage Reshaping with Carbon Dioxide Spray Cooling”, which will begin this summer in the research labs of Drs. Brian Wong, Stuart Nelson, Wangcun Jia and Dmitry Protsenko at the Beckman Laser Institute. Congratulations Ed!

BLI Physicians are recognized by the Orange County Medical Association

Dr. Brian Wong

Dr. Kristen Kelly, Dermatology, and Dr. Brian Wong, Otolaryngology/Head and Neck Surgery, were recently recognized by the Orange County Medical Association as “Physicians of Excellence.”

Every year, the Orange County Medical Association conducts a comprehensive survey of local physicians and rates them on leadership, teaching, mentoring, research and humanitarian service. Physicians honored are listed in the January 2010 issue of Orange Coast Magazine. Congratulations to Dr. Kelly and Dr. Wong!

Erin Miller Receives 2009 VBF Service Award

Erin Miller with Dr. Stuart Nelson

Each year, the Vascular Birthmarks Foundation (VBF) President, Linda Rozell-Shannon Ph.D., presents a Service Award to a deserving individual for "dedication and tireless energy in her work with families affected by vascular malformations." This year, the award was presented to Erin Miller, Beckman Laser Institute’s Development Director. For the past 5 years, Erin has worked with Dr. Shannon, Dr. J. Stuart Nelson and representatives of the VBF to coordinate the conference on the West coast as well as to volunteer to work during the conference when it has been located on the East coast.

The first year that BLI hosted the West coast conference was 2005 when Erin coordinated the details of the conference. In 2006, the conference was held in Boston where Erin helped facilitate the clinic appointments. In 2007, BLI hosted the VBF conference for the second time on the West coast at the Island Hotel with Erin responsible for the coordination of this conference.

Erin, Deb Birnie and Dr. Nelson traveled with Patricia Beckman to New York for the 2008 conference and worked in the clinic sessions there.

This year, on October 9 & 10, BLI again hosted the conference on the West coast. This year's event produced a record attendance (300) and was the most successful VBF conference to date. Congratulations to Erin.

Professor Brian Wong Awarded New Grant


Professor Wong (left) with his research group

Brian J.F. Wong, MD,PhD, Professor and Director of Facial Plastic Surgery at the University of California Irvine received a three year $830,000 grant from the Department of Defense to investigate novel methods to control cartilage warping in costal cartilage grafts. Extensive study of using lasers to generate heat by the Dr. Wong and his colleagues at the University of California, Irvine, led directly to a spin-off technology, referred to as electromechanical reshaping (EMR) or electroforming. EMR is a novel and patented tissue reshaping technique that may allows surgeons to bend cartilage into the shape they desire by simply inserting platinum plated needles, then applying electrical current from a source as common as a disposable battery. The process does not involve heat generation and instead relies upon redox reactions in the tissue to alter stress and strain relationships. EMR will potentially provide surgeons with a new way to change the shape of cartilage tissue in a much more elegant manner without having to crush, carve, or suture.

The Most Transparent Research

Dr. Choi

Professor Bernard Choi's work on "optical clearing" is highlighted in Nature Medicine.

Nature Article
Dr. Choi's Profile
Choi Lab Website

New biophotonics techniques hold promise but need translation, say researchers at NIH-SPIE 'Bench to Bedside' workshop

http://spie.org/x37689.xml

BETHESDA, Maryland, USA, and BELLINGHAM, Washington, USA -- Leading-edge advances such as a revolutionary cardiology treatment and noninvasive optical techniques for studying the brain combined with pragmatic discussions on research focus and funding highlighted a two-day inter-institute workshop last week at the National Institutes of Health (NIH) in Bethesda, Maryland.

Approximately 350 preeminent researchers in biophotonics attended the workshop, titled "Optical Diagnostics and Biophotonic Methods from Bench to Bedside." Amir Gandjbakhche, NIH, and Bruce Tromberg, Beckman Laser Institute and Univ. of California, Irvine, chaired the meeting, held 1-2 October. SPIE provided logistical support for the event.

Attendees including Christopher Contag, Stanford Univ. School of Medicine, and Joseph Izatt, Duke Univ., characterized the event as an extremely informative and valuable opportunity for candid discussion among the key players about the newest developments in the field.

The workshop's 30 oral presentations covered the latest optical techniques for diagnosis of diseases of the eye, brain, breast, and vascular system, and developments in endoscopy, molecular probes, and applications to stem-cell research.

Tromberg's opening remarks outlined the barriers to translation of optical technologies from the research bench to clinical use. He noted that of more than 50,000 clinical trials surveyed, "only a few percent involved lasers or optical technologies." He said that this low percentage is "a result of our community's focus primarily on technology development and early feasibility studies. Our next great challenge is to expand our impact and pursue phase 1-3 studies that standardize and validate new technologies and demonstrate clinical efficacy."

Guillermo Tearney, Massachusetts General Hospital, and Joseph Schmitt, LightLab Imaging, told about the revolutionizing impact of the recent introduction of Fourier transform optical coherence tomography (FT OCT) on the field of intracoronary imaging in interventional cardiology. The key advancement of this technique is in the speed of image acquisition, allowing examination of the interior of arteries without the use of a balloon to halt blood flow during imaging.

Tearney and Schmitt said the technology is moving rapidly to clinical use in Europe and Japan. Although it is not yet approved in the U.S., they predict it will become the FDA standard evaluation tool for all future stent procedures.

Christoph Hitzenberger, Center for Biomedical Engineering and Physics, Medical Univ. of Vienna, reported on diagnosis of diseases of the eye utilizing the latest high-resolution OCT, with isotropic resolution of 5 micron^3 (5x5x5 microns).

Anita Mahadevan-Jansen, Vanderbilt Univ., described infrared neural stimulation based on pulsed infrared light, for providing a noninvasive replacement method for electrical stimulation in diagnostic and therapeutic applications for brain and neural research.

Strong panel discussions addressed cost effectiveness and performance efficacy of new technologies compared to current practice, and sparked more discussion of barriers to new-technology translation, e.g., the limited time medical professionals have for new developments relative to their daily clinical activities, and the lack of effective image-interpretation tools to connect the new images with clinicians' experience-based procedures.

NIH funding directors Houston Baker, Yantian Zhang, and Debra Babcock told attendees that 90% of NIH funding goes to investigator-initiated grants and only 10% to agency announcements. They urged institutes to connect with NIH staff about possible opportunities.

Tayyaba Hasan, Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School, was presented with the NIH Bench-to-Bedside Pioneer Award for her extraordinary contributions to the field of biomedical optics including her work in photodynamic therapy (PDT), clinical translation of technology, and extensive mentoring of young scientists.

Best Student Poster prizes chosen from among the nearly 100 entries from young researchers went to Rabah Al Abdi, SUNY Downstate Medical Center (first); Abhishek Rege, Johns Hopkins Univ. (second); and Sarah Erickson, Florida International Univ. (third).

SPIE is the International Society for Optics and Photonics, founded in 1955 to advance light-based technologies. Serving more than 188,000 constituents from 138 countries, the Society advances emerging technologies through interdisciplinary information exchange, continuing education, publications, patent precedent, and career and professional growth. SPIE annually organizes and sponsors approximately 25 major technical forums, exhibitions, and education programs in North America, Europe, Asia, and the South Pacific, and supports scholarships, grants, and other education programs around the world. For more information, visit SPIE.org.


# # # #
Media contact:
Amy Nelson
Public Relations Manager
+1 360 685 5478
amy@spie.org

Dr. Bernard Choi Honored by ESC

Link to Engineering Announcement

BLI Medical Student Ed Wu Awarded ASLMS Research Grant

Ed Wu

The American Society for Laser Medical and Surgery (ASLMS) announced today that UCI School of Medicine medical student Ed Wu, who is in the MD MBA program, has just been awarded one of only four ASLMS Student Research Grants. The award of $5,000 will support Ed’s research project, “Laser Auricular Cartilage Reshaping with Carbon Dioxide Spray Cooling”, which will begin this summer in the research labs of Drs. Brian Wong, Stuart Nelson, Wangcun Jia and Dmitry Protsenko at the Beckman Laser Institute. Congratulations Ed!

BLI Physicians are recognized by the Orange County Medical Association

Dr. Brian Wong

Dr. Kristen Kelly, Dermatology, and Dr. Brian Wong, Otolaryngology/Head and Neck Surgery, were recently recognized by the Orange County Medical Association as “Physicians of Excellence.”

Every year, the Orange County Medical Association conducts a comprehensive survey of local physicians and rates them on leadership, teaching, mentoring, research and humanitarian service. Physicians honored are listed in the January 2010 issue of Orange Coast Magazine. Congratulations to Dr. Kelly and Dr. Wong!

Erin Miller Receives 2009 VBF Service Award

Erin Miller with Dr. Stuart Nelson

Each year, the Vascular Birthmarks Foundation (VBF) President, Linda Rozell-Shannon Ph.D., presents a Service Award to a deserving individual for "dedication and tireless energy in her work with families affected by vascular malformations." This year, the award was presented to Erin Miller, Beckman Laser Institute’s Development Director. For the past 5 years, Erin has worked with Dr. Shannon, Dr. J. Stuart Nelson and representatives of the VBF to coordinate the conference on the West coast as well as to volunteer to work during the conference when it has been located on the East coast.

The first year that BLI hosted the West coast conference was 2005 when Erin coordinated the details of the conference. In 2006, the conference was held in Boston where Erin helped facilitate the clinic appointments. In 2007, BLI hosted the VBF conference for the second time on the West coast at the Island Hotel with Erin responsible for the coordination of this conference.

Erin, Deb Birnie and Dr. Nelson traveled with Patricia Beckman to New York for the 2008 conference and worked in the clinic sessions there.

This year, on October 9 & 10, BLI again hosted the conference on the West coast. This year's event produced a record attendance (300) and was the most successful VBF conference to date. Congratulations to Erin.

Professor Brian Wong Awarded New Grant


Professor Wong (left) with his research group

Brian J.F. Wong, MD,PhD, Professor and Director of Facial Plastic Surgery at the University of California Irvine received a three year $830,000 grant from the Department of Defense to investigate novel methods to control cartilage warping in costal cartilage grafts. Extensive study of using lasers to generate heat by the Dr. Wong and his colleagues at the University of California, Irvine, led directly to a spin-off technology, referred to as electromechanical reshaping (EMR) or electroforming. EMR is a novel and patented tissue reshaping technique that may allows surgeons to bend cartilage into the shape they desire by simply inserting platinum plated needles, then applying electrical current from a source as common as a disposable battery. The process does not involve heat generation and instead relies upon redox reactions in the tissue to alter stress and strain relationships. EMR will potentially provide surgeons with a new way to change the shape of cartilage tissue in a much more elegant manner without having to crush, carve, or suture.

The Most Transparent Research

Dr. Choi

Professor Bernard Choi's work on "optical clearing" is highlighted in Nature Medicine.

Nature Article
Dr. Choi's Profile
Choi Lab Website

New biophotonics techniques hold promise but need translation, say researchers at NIH-SPIE 'Bench to Bedside' workshop

http://spie.org/x37689.xml

BETHESDA, Maryland, USA, and BELLINGHAM, Washington, USA -- Leading-edge advances such as a revolutionary cardiology treatment and noninvasive optical techniques for studying the brain combined with pragmatic discussions on research focus and funding highlighted a two-day inter-institute workshop last week at the National Institutes of Health (NIH) in Bethesda, Maryland.

Approximately 350 preeminent researchers in biophotonics attended the workshop, titled "Optical Diagnostics and Biophotonic Methods from Bench to Bedside." Amir Gandjbakhche, NIH, and Bruce Tromberg, Beckman Laser Institute and Univ. of California, Irvine, chaired the meeting, held 1-2 October. SPIE provided logistical support for the event.

Attendees including Christopher Contag, Stanford Univ. School of Medicine, and Joseph Izatt, Duke Univ., characterized the event as an extremely informative and valuable opportunity for candid discussion among the key players about the newest developments in the field.

The workshop's 30 oral presentations covered the latest optical techniques for diagnosis of diseases of the eye, brain, breast, and vascular system, and developments in endoscopy, molecular probes, and applications to stem-cell research.

Tromberg's opening remarks outlined the barriers to translation of optical technologies from the research bench to clinical use. He noted that of more than 50,000 clinical trials surveyed, "only a few percent involved lasers or optical technologies." He said that this low percentage is "a result of our community's focus primarily on technology development and early feasibility studies. Our next great challenge is to expand our impact and pursue phase 1-3 studies that standardize and validate new technologies and demonstrate clinical efficacy."

Guillermo Tearney, Massachusetts General Hospital, and Joseph Schmitt, LightLab Imaging, told about the revolutionizing impact of the recent introduction of Fourier transform optical coherence tomography (FT OCT) on the field of intracoronary imaging in interventional cardiology. The key advancement of this technique is in the speed of image acquisition, allowing examination of the interior of arteries without the use of a balloon to halt blood flow during imaging.

Tearney and Schmitt said the technology is moving rapidly to clinical use in Europe and Japan. Although it is not yet approved in the U.S., they predict it will become the FDA standard evaluation tool for all future stent procedures.

Christoph Hitzenberger, Center for Biomedical Engineering and Physics, Medical Univ. of Vienna, reported on diagnosis of diseases of the eye utilizing the latest high-resolution OCT, with isotropic resolution of 5 micron^3 (5x5x5 microns).

Anita Mahadevan-Jansen, Vanderbilt Univ., described infrared neural stimulation based on pulsed infrared light, for providing a noninvasive replacement method for electrical stimulation in diagnostic and therapeutic applications for brain and neural research.

Strong panel discussions addressed cost effectiveness and performance efficacy of new technologies compared to current practice, and sparked more discussion of barriers to new-technology translation, e.g., the limited time medical professionals have for new developments relative to their daily clinical activities, and the lack of effective image-interpretation tools to connect the new images with clinicians' experience-based procedures.

NIH funding directors Houston Baker, Yantian Zhang, and Debra Babcock told attendees that 90% of NIH funding goes to investigator-initiated grants and only 10% to agency announcements. They urged institutes to connect with NIH staff about possible opportunities.

Tayyaba Hasan, Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School, was presented with the NIH Bench-to-Bedside Pioneer Award for her extraordinary contributions to the field of biomedical optics including her work in photodynamic therapy (PDT), clinical translation of technology, and extensive mentoring of young scientists.

Best Student Poster prizes chosen from among the nearly 100 entries from young researchers went to Rabah Al Abdi, SUNY Downstate Medical Center (first); Abhishek Rege, Johns Hopkins Univ. (second); and Sarah Erickson, Florida International Univ. (third).

SPIE is the International Society for Optics and Photonics, founded in 1955 to advance light-based technologies. Serving more than 188,000 constituents from 138 countries, the Society advances emerging technologies through interdisciplinary information exchange, continuing education, publications, patent precedent, and career and professional growth. SPIE annually organizes and sponsors approximately 25 major technical forums, exhibitions, and education programs in North America, Europe, Asia, and the South Pacific, and supports scholarships, grants, and other education programs around the world. For more information, visit SPIE.org.


# # # #
Media contact:
Amy Nelson
Public Relations Manager
+1 360 685 5478
amy@spie.org