BLIMC Studies
IRB Document Depot
Inclusion/Enrollment

Protocol NumberPITitleApproval
1995-563-Bruce Tromberg, Ph.D.Measurements of Breast Tissue Optical Properties3/09/17-3/08/18
Expedited Review
1996-190Yona Tadir, M.D.(CLOSED) PDT/Endometrial Ablation CLOSED 2001
Full Review
1996-200J. Stuart Nelson, M.D., Ph.D. (CLOSED) Optical Biopsy of Human Skin in Conjunction with Laser Treatment7/20/2008 Closed
expedite review
1999-2154 Kristen Kelly, MD(CLOSED) Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks at High Fluences2/23/2009 Closed
Full Review
1999-2183R. Holcombe, M.D./ B.Tromberg, PhD(CLOSED) Non-Invasive Functional Mapping of Breast tissue Physiology Using Quantitative Near-Infrared Spectroscopy: Effects of Selective Estrogen Receptor Modulators (A Pilot Study Subset of the STAR NSABP Protocol P-2)3/10/2004 closed
Full Review
1999-2250J. Stuart Nelson, M.D., Ph.D. (CLOSED) Measurement of Human Skin Temperature During Pulsed Laser Exposure3/9/2010 Closed
expedite review
2000-1449Glenn Healey, PhD (CLOSED) Using Hyperspectral Images for Human Identification at a Distance 12/2/2003 Closed
expedite review
2000-1506Kristine Kelly, MD(CLOSED) Effect of wavelength on laser treatment of port wine stain birthmarks 1/17/2003 Closed
Full Review
2001-1703Kristine Kelly, MD(CLOSED) Effect of Pulse Duration on Laser Treatment of Vascular Lesion 2/21/2003 Closed
Full Review
2001-1924D.Cooper, M.D/B.Tromberg, PhD(CLOSED) Delayed Onset Muscle Soreness in Children and Adults6/20/2003 Closed
expedite review
2001-2011Albert Cerussi, PhD(CLOSED) Measurements of Anemia and Physiologic Tissue Response to Blood Transfusions in VLBW Infants Using Quantitative NIRS9/22/2008 Closed
expedite
2002-2306D.Hsiang, MD/B.Tromberg,PhD(CLOSED) Monitoring the Response of Chemotherapy on Breast Cancer Tumor by Photon Migration Spectroscopy1/24/2011 Closed
Full Review
2002-2608Virginia Kimonis & Burce Tromberg(CLOSED) Mitochondria inborn errors of metabolism and ANT defect in mitochodiral diseases 5/22/15 Closed
expedited
2002-2672Brian Wong, MD, PhD(CLOSED) Near-Infrared Transillumination of the Paranasal Sinuses2/20/2009 Closed
expedite review
2002-2805Petra Wilder-Smith, D.D.S., Ph.D.OCT-FDPM Photodynamic Detection of Oral Pathology2/9/17-2/8/18
expedited 4&5
2003-3025Brian Wong, M.D.,Ph.DOCT of Upper Areo-Digestive Tract06/03/2016-06/02/17
expedited 4
2003-3086Wangcun Jia, PhD(CLOSED) Treatment of Vascular Lesions with a Tandem 532/1064 nm Laser 11/17/2011 CLOSED
expedite review
2003-3200 Wangcun Jia,PhD (CLOSED) Cutaneous Effects of Cryogen Spray Cooling 8/26/2010 Closed
Full Review
2003-3286Kristen Kelly, MD(CLOSED) Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains 10/20/2014 Closed
Full Review
2003-3442Kristen Kelly, MD(CLOSED) Optical clearing of the skin in conjunction with laser treatments7/24/2008 Closed
Full Review
2004-3555Baruch Kuppermann, M.D., Ph.D./Zhongping Chen,PhD(CLOSED) A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging7/5/2013 CLOSED
expedite review
2004-3626Bruce Tromberg, Ph.D.Distribution of Optical Properties in Adult Human Muscle6/17/16-6/16/17
expedited
2004-3993Brian Wong, MD, PhDAnthromometric Analysis of the Ethnic Face2/12/16-2/11/19
Exempt review
2005-4505Pietro Galassetti, MD, PhD Biomarkers of glucose metabolism in exhaled breath3/6/15-3/5/16
expedite review
2005-4675Doug Wallace, PhD(CLOSED) Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort8/13/2010 CLOSED
Full Review
2005-4760Bruce J. Tromberg, PhD(CLOSED) Monitoring Functional Variations in the Breast during the Menstrual Cycle by using Diffuse Optical Spectroscopy 10/18/2012 Closed
expedite review
2005-4775Mark Linskey, MD,/B ruce Tromberg, PhD(CLOSED) Monitoring Neural Tissues Properties by Modulated imaging5/19/2009 Closed
Full Review
2006-4815Kristen Kelly, MD(CLOSED) Combining topical imiquimod 5% cream with a pulsed dye laser to treat port wine stain birthmarks8/18/2012 CLOSED
Full Review
2006-4876Pietro Galassetti, MD, PhD (PENDING) Exercise and Oxidative Stress Mechanism
Full Review
2006-4981Matthew Brenner, MD(CLOSED) OCT for Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer.CLOSED 3/25/16
Full Review
2006-4982Mathew Brenner, M.DOCT of airway and pleural disorder10/26/16-10/25/17
Expedited Review
2006-4992J. Stuart Nelson, M.D., Ph.D. (CLOSED) Combined alexandrite and pulsed dye laser treatment of port wine stain birthmarks4/21/2011 CLOSED
Full Review
2006-5031Marlon Mathews, MD/Zhongping Chen,PhD(CLOSED) Optical Coherence Tomography Imaging of post coil aneurysm healing4/07/2012 Closed
Full Review
2006-5108Petra Wilder Smith, DDS, PhD (CLOSED)Analysis of Biofilms in Wound tissue9/17/2007 CLOSED
expedite review
2006-5138Kristen Kelly, MD(CLOSED)Evaluation of the Candela 1064nm Nd:YAG laser for Treatment 4/22/2010 CLOSED
Full Review
2006-5191Matthew Brenner, MD.(CLOSED) Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans12/15/2011 Closed
expedite review
2006-5401J. Stuart Nelson, M.D., Ph.D. (CLOSED) Pulsed dye laser treatment of port wine stain birthmarks: Comparison of 577 nm vs 595 nm wavelengths2/23/2009 Closed
Full Review
2007-5572Madeleine Pahl, M.D/ William Mantulin Ph.D(CLOSED) Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in CKD3/23/2012 CLOSED
expedite review
2007-5691JS Nelson, MD, PhD(CLOSED) Incidence of ocular antibodies in patients with Sturge-Weber Syndrome6/16/2008 Closed
Full Review
2007-5832Virginia Kimonis, M.D./ Bruce Tromberg, PhDCharacterization of Familial Myopathy and Paget Disease of Bone8/26/16-8/25/17
Full Review
2007-5891Even Gregory, MD and Anthony Durkin, PhDMonitoring of tissue transfer flaps by MI spectroscopy01/19/2017-01/18/2018
expedited 4,5,6
2007-5947William Mantulin Ph.D. (CLOSED) ABSOLUTE NEAR INFRARED BRAIN OXIMETER10/8/2010 CLOSED
Full Review
2007-6094Kristen Kelly, M.D.Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target8/12/16-8/11/17
Expedited category 5
2007-6098J. Stuart Nelson, M.D., Ph.D. (CLOSED) Combined pulsed dye laser and topical ranibizumab for treatment of port wine stain birthmarks 11/1/2013 CLOSED
Full Review
2008-6099David Hsiang MD(CLOSED) A Pilot Study to Evaluate the Correlation of Modified Two Layer Diffuse Optical Spectroscopy (MTL DOS), Multi-spectral Imaging (MI), and Spatially Modulated Quantitative Spectroscopy (SMoQs) as Compared to Clinical Examination and Histological of Pigmented Skin Lesions based on Physiological Parameters1/17/2014 CLOSED
expedite review
2008-6307Kristen Kelly, M.D. Skin Imaging with Technologies in Development05/27/16-05/26/17
Full Review
2008-6309J. Stuart Nelson, M.D., Ph.D. (CLOSED) Combined pulsed dye laser and topical tacrolimus for treatment of port wine stain birthmarks 7/20/2008 CLOSED
Full Review
2008-6355Petra Wilder Smith, DDS, PhD (CLOSED) The Investigation of a Fluorescence/Elastic Scattering Spectroscopy Device for Oral Tissue Characterization6/1/2011 Closed
expedite review
2008-6383J. Stuart Nelson, M.D., Ph.D.(CLOSED) Combined pulsed dye laser and rapamycin treatment of port wine stain birthmarks 1/6/2016 CLOSED
Full Review
2008-6415Ping Wang, M.D./Bruce J. Tromberg, Ph. D(CLOSED) Vascular Reactivity in Metabolic Syndrome and Diabetic Patients Using Diffuse Optical Spectroscopy 10/21/2013 CLOSED
expedite review
2008-6439Kristen Kelly, MD(CLOSED) Determining Optical Properties of Cutaneous Neoplastic Diseases and Photosensitizing Agents via Structured illumination and Real-time Dosimetry9/28/2012 Closed
expedite review
2008-6549Edward Nelson, M.D./Bruce Tromberg, PhD(CLOSED) Study of chemotherapy side effects in cancer patients: non-invasive optical measurements of the brain4/24/2012 Closed
expedite review
2008-6593Brian Wong, MD, PhD(CLOSED) Minimally Invasive Holmium:YAG laser Blepharoplasty8/8/2014 Closed
Full Review
2008-7204Brian Wong, MD, PhD(CLOSED) Use of Resorbable Plates in Repair of Orbital Floor Fractures1/14/2011 CLOSED
expedite review
2009-6996Christopher Zachary, FRCP, MBBS(CLOSED) A RANDOMIZED, EVALUATOR-BLINDED, PARALLEL GROUP COMPARISON OF PHOTODYNAMIC THERAPY WITH LEVULAN® TOPICAL SOLUTION + BLUE LIGHT Versus LEVULAN® TOPICAL SOLUTION VEHICLE + BLUE LIGHT FOR THE TREATMENT OF ACTINIC KERATOSES AND REDUCTION OF NEW NON-MELANOMA SKIN CANCER ON THE SCALP OR BOTH FOREARMS IN ORGAN TRANSPLANT RECIPIENTS7/19/2100 CLOSED
Full Review
2009-7046Willem Verkruysse, Ph.D(CLOSED) A pilot study using photo-plethysmographic camera to monitor heart rate, respiration rate and9/28/2009 Closed
expedite review
2009-7050Bernard Choi, PhD(CLOSED) A Pilot Study using Laser Speckle Imaging of Neonate Cerebral Vasculature9/2/2010 Closed
expedite review
2009-7069J. Stuart Nelson, M.D., Ph.D. (CLOSED) Combined use of pulsed dye laser and topical antiangiogenic agents for treatment of port wine stain birthmarks 9/10/2011 Closed
Full Review
2009-7204Brian Wong, MD, PhD(CLOSED) Use of Resorbable Plates in Repair of Orbital Floor Fractures1/14/2011 CLOSED
expedite review
2009-7245Wangcun Jia, PhD(CLOSED) Pain Blocking during Drug Administration or Blood Collection with Needles2/24/2014 Closed
expedite review
2009-7262J. Stuart Nelson, M.D., Ph.D. (CLOSED) Pilot Study on the use of the EMatrix RF (radiofrequency) for treatment of port wine stain birthmarks 10/13/2011 CLOSED
Full Review
2009-7322Tony Durkin, PhD Ability of modulated imaging and laser speckle imaging to determine burn wound severity and healing potential5/5/16-5/4/17
Expedited
2010-7376Bernard Choi, PhDMonitoring the response of port wine stain birthmarks to laser therapy with wide-field functional imaging technologies under development2/11/16-2/10/17
Expedited
2010-7454Enrico Gratton, PhD.(CLOSED)Coordination of the frontal lobes perfusion and the motor-sensory cortex in5/11/2011 CLOSED
expedite review
2010-7521Lingzhong Meng, MD/Albert Cerussi, Ph.D. (CLOSED) Assessing Cerebrovascular Reactivity based on Cerebral Oximetry: a Pilot Study12/20/2011 Closed
expedite review
2010-7780Kristen Kelly, MD(CLOSED) Patient satisfaction survey regarding treatment of port wine stains11/17/2013 CLOSED
Exempt review
2010-7789Bruce Tromberg, Ph.DPredicting pathological response within the first week of neoadjuvant chemotherapy using functional parameters measured with Diffuse Optical Spectroscopy imaging9/23/16-9/22/17
Full Review
2010-7812Bruce Tromberg, PhDMonitoring and Predicting Breast Cancer Neoadjuvant Chemotherapy Response Using Diffuse Optical Spectroscopic Imaging (DOSI) 10/17/14-10/16/15
expedited
2010-7851Kristen Kelly, MD(CLOSED) Role of Metabolic Enzymes in Skin: Potential for Informative Biomarkers and Therapeutic TargetsCLOSED
Full Review
2010-7852Bruce J. Tromberg, PhD(CLOSED) Monitoring Chemotherapy Response of Soft Tissue Sarcomas and Osteosarcomas using Diffuse Optical Spectroscopic Imaging 11/17/2014 Closed
expedite review
2010-7886Jennifer Holtzman, DDS, MPH (CLOSED) Effect of Dietary Nutrients on Oral Quality of Life12/1/2012 CLOSED
expedite review
2010-8002Brian Wong, MD, PhD(CLOSED) Ultrasonographic Assessment of External Framework Rhinoplasty with Injectable Hyaluronic Acid2/1/2012 CLOSED
expedite review
2010-8015Elliot Botvinick, Ph.D(CLOSED) Spectroscopic Evaluation of Middle Ear Infection8/21/2013 CLOSED
expedite review
2010-8163Bernard Choi, Ph.D.(CLOSED) Noninvasive Optical Measurement of Critical Care Neonates5/25/2011 CLOSED
expedite review
2011-8028Brian Wong, MD, PhD(CLOSED) Evaluating the Effectiveness of Over-the-Counter Lip Enhancement Products8/27/14 CLOSED
expedite review
2011-8075Jun Zhang, PhD(CLOSED) Evaluation of obstructive sleep apnea with long range 3D endoscopic Fourier Domain Optical Coherence Tomography 3/21/2014 Closed
expedite review
2011-8163Bernard Choi, PhD.(CLOSED) Noninvasive Optical Measurement of Critical Care NeonatesCHOC 5/25/2011 CLOSED
expedite review
2011-8230Bruce Tromberg, Ph.D(CLOSED) In-vivo non-invasive skin imaging using multiphoton tomography and multi-spectral imaging for studying the effects of Renova cream and UVB irradiation on human skin8/14/2012 CLOSED
Full Review
2011-8243Petra Wilder Smith, DDS, PhD (CLOSED)Collection of oral tissue pathology related to cancer in India population for developing Optical Coherence Tomography 6/12/2014 CLOSED
Exempt review
2011-8295Naveen Bhandarkar, MDDevelopment and Validation of a NIRS-based Sinusitis Screening7/8/14-7/7/15
Expedite
2011-8370Anthony Durkin, PhDA Pilot Study to Evaluate Multi-Spectral Imaging (MI) and Laser Speckle Imaging (LSI) during Vascular Occlusion10/17/16-10/16/17
Expedite catergory 4,5,6
2011-8417Jennifer Holtzman DDS MPH(CLOSED) Prevalence of very early tooth decay in active adults 65+ years12/3/14 CLOSED
expedite review
2011-8494Kristen Kelly, MD Pilot study on in-vivo non-invasive skin imaging using multiphoton microscopy10/05/16-10/04/17
Expedite
2011-8536Kristen Kelly, MD(CLOSED) A Randomized, Placebo-Controlled Study of the 1320 nm Nd:YAG Laser for Improving the Appearance of Onychomycosis1/24/2014 CLOSED
Full Review
2011-8574Christopher Owen, MD(CLOSED) A Pilot Study using Laser Speckle Imaging of Adult Cerebral Vasculature during cerebrovascular surgery.12/15/2012 CLOSED
Exempt review
2012-8714Bruce TrombergDevelopment of a Quantitative Tissue Optical Index of Breast Density For Prediction of Hormone Therapy Response3/27/2017-3/26/2018
Expedited review
2012-8774Elliot L Botvinick, Ph.D(CLOSED) Evaluation of a new biocompatible pressure equalizing tube8/12/2014 Closed
Full Review
2012-8868Anthony Durkin, PhDAssessment of the Potential for Pressure Ulcer Formation using a new optical imaging technology7/8/15-7/7/16
Expedite
2012-9022Brian Wong, MD, PhD(CLOSED) Analysis of healing process in Rhinoplasty procedure8/21/14 CLOSED
Exempt review
2012-9075Matthew Brenner, M.D. DOS and other Non-Invasive Optical Spectroscopic Methods for Dehydration Identification in Marathon Trainees9/01/16-8/31/17
expedited
2012-9092J. Stuart Nelson, M.D., Ph.D. (CLOSED) Combined Bipolar Radiofrequency (RF) and Pulsed Dye Laser (PDL) Treatment of Port Wine Stain BirthmarksCLOSED
FULL review
2012-9094Wangcun Jia, PhDA Pilot study of Photo Acoustic Microscopy (PAM) and Optical Coherence tomography (OCT) Imaging Technologies to evaluate the port-wine stain birthmark treatment before and after pulsed dye laser (PDL) treatment.11/18/16-11/17/17
Expedite
2012-9140Margaret Schneider,Ph.D(CLOSED)Dissemination of Research Findings to Participants of ICTS-Supported Studies11/5/13 CLOSED
2012-9158Shaista Malik, MD, PhD &TrombergThe use of Diffuse Optical Spectroscopy to Characterize Adipose Tissue Oxygenation and Vascular Reactivity in Response to Weight-Loss Intervention1/8/15-1/7/16
expedited
2012-9270Madeleine Pahl, M.D/ William Mantulin Ph.D(CLOSED) Diffuse Optical Spectroscopy Imaging (DOSI) to Assess Volume Changes During Hemodialysis1/27/2015 CLOSED
expedite review
2013-9337Kristen Kelly, M.D.Novel Treatment for Port Wine Stain Birthmarks9/23/2016-9/22/2017
FULL review
2013-9363Ryan Leary/William Armstrong, MD Parotidectomy and Superficial Musculoaponeurotic System Interposition: A Twelve-Year Review of Operative Technique and Frey’s Syndrome Incidence3/14/13-3/13/16
Exempt review
2013-9396Winbin Tan, PhD.,John S Nelson, MDPathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples2/20/15-2/19/16
Full Review
2013-9435Michael E. Lekawa, MD./Albert Crussi, PhD.(CLOSED) Use of Portable Diffuse Optical Spectroscopy Technologies for Non-Invasive Hemodynamic Evaluation of Trauma/Critically Care Patients8/21/13 Closed
expedite review
2013-9473Bruce Tromberg, PhD(CLOSED) A Pilot Study to Investigate Non-Invasive Metabolic Guidance for Improving Therapeutic Ultrasound Treatment of Lower Back Muscle Injuries1/14/16 CLOSED
expedited
2013-9505Omid Fathi, MD,/Bernard Choi, PhD(PENDING) Measurement of neonatal microvascular hemodynamics using non-invasive optical technologies
expedited
2013-9778Petra Wilder- Smith,DDS.,PhDA Clinical and Imaging Study to Evaluate a Novel Dentifrice05/13/16-05/12/17
expedited
2014-1167Petra Wilder- Smith,DDS.,PhDNon-Invasive Oral Biofilm Characterization 12/22/2016-12/21/2017
full review
2014-1229Gregory Evans, M.D Predicting Breast Flap Necrosis by Spatial Frequency Domain Imaging9/26/2015-9/25/2017
Expedited
2014-1390Petra Wilder Smith DDS. PhD. Low-cost, noninvasive method to assess pulpal vitality9/19/16-9/18/17
expedited
2014-1505Bruce J. Tromberg, PhDBreast tumor oxygenation during exercise12/12/16-12/11/17
expedite
2014-1508Mihaela Balu, PhD In-vivo non-invasive skin imaging pilot study to assess the effects of tretinoin cream and Skin Smoothing Laser™ using multi-photon microscopy (MPM) and multi-spectral imaging (MI)04/08/16-04/07/17
Full Review
2015-1791Kristine Kelly, MDSpectral comparison between Spatially Modulated Quantitative Spectroscopy (SMoQS) and Polarization-Sensitive Hyperspectral Multimode Dermoscopy for the purpose of skin compositional analysis5/5/16-5/4/17
expedite
2015-1840Kristine Kelly, MDImmune-Related Trafficking and Signaling in Human Skin Associated with Low-Power, Infrared Laser Treatment 1/27/17-1/26/18
Full Review
2015-2252Mihaela Balu, PhDPilot study for in vivo multiphoton imaging of melanin in human skin10/23/2015-10/22/2016
Expedited Review
2015-2355Bruce Tromberg, PhDMonitoring and Predicting Breast Cancer Neoadjuvant Chemotherapy Response Using Diffuse Optical Spectroscopic Imaging in a Multi-Center Setting10/17/2016-10/16/2017
Expedited Review
2015-2490Brian WongFacial Plastic Surgery Chart Review06/29/2016-06/28/2017
Expedited
2016-2702Nadine Abi-JaoudehAssessment of revascularization surgery efficacy in the context of lower extremity ulcers using multiple diffuse optical techniques06/07/2016-06/06/2016
Expedited - Vascular