highlights and progress

• Team 1 is comprised of 6 core academic members, who utilize the infrastructure of 5 NCI comprehensive cancer centers, 4 NCRR P41 Technology Centers, and 2 NCI P01 program projects.
• The BC-DOI network includes 41 Associate Members from 10 Academic and 11 Industry sites.
• Over 40 students have participated in BC-DOI organized meetings in the past year.
• Team 1 organized 2 scientific sessions at national meetings, held 8 Executive Committee Conference calls, and presented at 4 international scientific meetings and 2 NIH sponsored meetings (13th Annual SPORE and NCI NTROI Meeting).
• Team 1 Investigators gave 15 presentations about research progress at 9 scientific meetings.
• Team 1 investigators filed 4 patent disclosures during this report period. The BC-DOI team has just completed licensing of about 40 United States patents for breast cancer detection to FirstScan, a spinoff company of Spectros, Inc, that formed specifically to work with NTROI and advance optical technology in breast cancer.
• Almost 100 scientists, clinicians, students, and members of industry from 8 states and 4 countries attended our Third Annual BC-DOI Network Retreat, presenting 23 posters and 18 talks.
• BC-DOI Network Investigators submitted 10 proposals to various agencies with the aim of leveraging NTROI funding.
• Team 1 clinical sites enrolled a total of 144 patients in BC-DOI studies.
• Team 1 awarded 9 developmental projects with $250,000 in total costs to continue work towards specific aims. The awarded developmental projects, aimed at contributing new understanding to primary objectives of the RFA, translation and validation, cover a broad spectrum of activities including database development, standardization of histopathology methods, development of novel measurement protocols, and support for student training.
• Team 1 developed 2 software platforms for databasing, data analysis, and data visualization optimized for optical imaging and optics-MRI co-registration in collaborations with RSNA and CA-BIG.
• BC-DOI Investigators cited NTROI research in 32 publications. A list of publications follows the progress report summary for each project and core.