Advanced nonlinear microscopy imaging tools and microbeam technologies are used to visualize and study tissue composition, architecture, mechanobiology and pathology.  The objective to using these tools are to advance technologies that enable better chemical contrast, expand imaging over wider and deeper length scales, reduce the time it takes to image and develop tools for studying interactions of the cells.

Optical microscopy and laser microbeams provide essential tools in molecular, cellular, and developmental biology, neuroscience, biophysics and biotechnology.  UCI enjoys a strong tradition in the field of optical microscopy and focused laser microbeams, and faculty members have pioneered many of the optical techniques that are now standard research tools in the biological sciences.

These research efforts cross departmental lines and unite the strengths of diverse research groups in Biomedical Engineering, Chemistry, Chemical Engineering & Materials Science, Developmental & Cell Biology, Neurobiology & Behavior and Physiology & Biophysics.  Cutting-edge advances span the development of state-of-the-art fluorescence correlation methods, nonlinear optical imaging, and laser microbeam technologies combined with their applications to investigate biological processes, as well as to probe and manipulate cells and tissues on extremely small scales.

Affiliated Faculty

Enabling Technologies

Clinical Impact

Selected Publications

Relevant Links