Biomedical Engineering Department
Cockrell School of Engineering
The University of Texas at Austin
Stories of Innovating Photomedicine in Neurology, Cardiology and Cancer
Although photomedicine has provided tremendous clinical advancements in dermatology and ophthalmology over the last three decades, innovations in neurology, cardiology, and cancer have been slower-paced. The human eye is a window to the brain and provides an opportunity to detect neuropathies by probing the retina with near infrared light. Recent advances that leverage the enormous information bandwidth of light suggest that exciting opportunities for early detection of various neuropathies such as Alzheimer’s disease may be possible. Although optical imaging of coronary arteries has been available for nearly two decades, adoption by cardiologists has been slow. Innovative light-based diagnostics that utilize machine learning allow expert’s prior knowledge to enhance image interpretation and better plan therapy. Advances in crossing chronic total occlusions in coronary arteries may resolve one the greatest challenges facing cardiologists today. Brain tumors near eloquent structures present the surgeon challenges for resection. Innovative light-based diagnostic and surgical tools for cancer detection and tumor resection that maintain a blood-free surgical field while providing high-speed sub-millimeter cutting precision can advance the art of micro neurosurgery.
Dr. Milner is a one of the early investigators in photomedicine having made seminal contributions in both surgery and diagnostics. He is one of the inventors of dynamic cooling of tissues that has substantially improved the practice of many laser dermatological treatments. Milner co-invented a device to reshape cartilage and introduced an optical clearing approach that allows the delivery of light to deeper structures in tissues. Milner and his collaborators at the Beckman Laser Institute were first to publish an approach called optical Doppler tomography which has provided the basis for light-based micro-angiography of the retina and other tissues. He has developed and demonstrated novel catheters for intravascular imaging and is a co-inventor of the MasSpec Pen that has been featured worldwide. Dr. Milner has been a pioneer in introducing novel endogenous contrast mechanisms for optical imaging of tissue. Milner won the Coherent Young Investigator Award in Biomedical Optics (2002) and is a Fellow of the ASLMS, AIMBE and the National Academy of Inventors.
For more information or to schedule a meeting with the speaker, please contact Hanna Kim.
Hosted by Dr. Bernard Choi